PODCAST. Entrepreneurship, Cannabis, and Psychedelics with April Pride

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April Pride interview.

April Pride on Integrity, Psychedelics, and the ADHD Entrepreneur’s Path

Hello, Wise Squirrel, for ADHD Awareness Month, I sat down with April Pride, a Seattle-based creative entrepreneur and harm reduction advocate known for building category-defining brands at the edges of lifestyle, cannabis, psychedelics, and women’s well-being. Our conversation ranged from accessible education and safety to the messy realities of addiction, partnerships, and late ADHD diagnosis. It’s rich, personal, and full of practical wisdom without drifting into prescriptions or hype.

This article sketches the contours of that discussion. If it resonates, hit play and hear April in her own words.

Why Integrity Comes First

April is clear about her lane. She isn’t a clinician or a facilitator. Her work lives in education and product design, informed by harm reduction and legality. When the business environment around psilocybin turned murky, she pressed pause rather than compromise her ability to speak openly. One line stayed with me: leaders in emerging spaces have a responsibility “not to mislead others.” That stance anchors the entire episode. I wish others would get that message.

Rethinking Access and Cost

SetSet, April’s current platform, grew from a simple question: how do you help the many people experimenting with psychedelics outside clinics do it more thoughtfully and affordably? We talk about integration tools that help translate insights into daily life, a therapist-designed microdosing framework, and why low-cost, evergreen resources can meet people where they are. The theme isn’t evangelism; it’s literacy.

ADHD, Dopamine, and Doing the Work

Diagnosed with ADHD at 38, April describes how treatment and structure unlocked bigger bets. She also opens up about developing cannabis use disorder when access became effortless, and what it took to step back. If you’ve ever used speed of execution as a superpower only to overheat the engine, you’ll recognize the pattern. We discuss healthier ways to chase stimulation, including movement, mindfulness, public speaking, creative expression, and the small daily practices that keep attention focused in the right direction.

Set and Setting, With Nuance

Safety comes up often. We discuss trip sitters, emotional readiness, and why timing matters. April highlights emerging observations around women’s hormonal cycles and challenging experiences, not as hard rules but as factors to weigh when planning. The simple takeaway: mindset and environment shape outcomes more than most people realize.

Partnerships, Burnout, and Learning Out Loud

April’s career includes multiple exits and a few misfires. She’s candid about over-delegating early, choosing partners to “complete” her gaps, and how coaching and clearer agreements changed the way she builds. If you’re a solo operator who “does it all” until something breaks, you’ll find practical perspective in how she now approaches scope, cadence, and fit.

Late Diagnosis and Making Peace with the Past

We spend time on the grief many feel after a late ADHD diagnosis: the could-have-beens, the self-talk that lingers, the habit loops that are hard to unwind. April shares how mindfulness, microdosing frameworks, and integration practices helped her cultivate self-respect and forward motion. It’s honest, grounded, and never presented as a magic fix. Dave also shares his take on how he managed his late diagnosis.

What You’ll Hear In The Episode

  • How April defines her role in psychedelics and why integrity guides product and messaging

  • Where integration fits, and why accessible tools matter for non-clinical users

  • A candid account of substance overuse and the systems she built to recover focus

  • Practical safety notes on set, setting, sitters, and personal readiness

  • Lessons from partnerships and exits that will save founders time and heartache

  • A humane look at ADHD, dopamine, and building better feedback loops

Why Listen

This isn’t a “guru” playbook. It’s a thoughtful conversation with a builder who has been early, been right, and been humbled, and who continues to design for real people. If you work at the edge of new markets, live with ADHD, or just want a clearer way to think about psychedelics without the noise, you’ll find signal here. Of course, we always advise speaking with a medical professional first.

🎧 Listen to the full episode of Wise Squirrels with April Pride to hear the stories, examples, and tactics we only hint at above.

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Wise Squirrels is Sponsored by Littlebird and Inflow.

Dave

🇨🇦+🇮🇪=🇺🇸

https://davedelaney.me
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PODCAST. Acting, Comedy, and Addiction with ADHD Big Brother, Russ Jones.