Dr. Stephen Faraone: What the Evidence Actually Says About ADHD.

Dr. Stephen Faraone Phd is a Distinguished Professor in the Psychiatry and Neuroscience & Physiology departments at the Norton College of Medicine at SUNY Upstate Medical University, Senior Scientific Advisor to the Research Program in Pediatric Psychopharmacology at Massachusetts General Hospital, and a lecturer at Harvard Medical School. He is President of the World Federation for ADHD and Program Director of adhdinadults.com and ADHDevidence.org.

In 2025, ScholarGPS ranked him the world's number-one ADHD scholar. He's in the top 0.01% of cited scientists across all fields.

He got into ADHD by accident. While doing a postdoc in psychiatric epidemiology and genetics, he met a colleague studying ADHD who needed a geneticist โ€” and stayed for 40 years.

This episode of Wise Squirrels covers a lot of ground, and Dr. Faraone doesn't hedge:

Adult ADHD barely existed as a diagnosis in the late 80s. The belief was that it stopped in adulthood. Then parents started turning up at the children's clinic saying, "I think I'm like my kid."

Symptoms shift, they don't vanish. Hyperactivity and impulsivity tend to diminish with age; inattention stays stable or increases. Most people move from combined presentation to inattentive, while few remain in the predominantly hyperactive presentation.

Pills don't replace skills. Medication is first-line treatment in the guidelines, and the evidence for FDA-approved ADHD medication is decades deep, but if you've been untreated for years, there are skills you still have to learn.

Drug holidays don't hold up. "If the disorder takes the holiday, the drug can take a holiday. But the disorder doesn't take a holiday." ADHD is 24/7, and people off medication have more accidents.

The trauma claim is backward. Dr. Faraone takes direct aim at the idea that ADHD is caused by childhood trauma. The genomic data suggests the opposite direction: children with higher genetic risk for ADHD are more likely to experience abuse and trauma. Genes push people into environments โ€” which is not the same as trauma causing the condition. Donโ€™t believe celebrity doctors who get paid for their misinformation and disinformation, like Gabor Matรฉ.

ADHD is not an American invention. Two doctors in Germany and Scotland described what we now recognize as ADHD in the late 18th century, which was long before any pharmaceutical company existed. Tipping our hat to Dr. Melchior Adam Weikard (1775) and Dr. Sir Alexander Crichton (1798).

And it isn't an evolutionary superpower. Working with geneticists in Barcelona, Faraone's team computed ADHD genomic risk from Paleolithic DNA. Those variants have been slowly eliminated from the human genome over tens of thousands of years, which is not what you'd expect from a trait that helped hunters survive. As he puts it: if you were inattentive, the lion got you.

ADHD ISnโ€™t A SUPERPOWER!

Dave pushes back on thinking that ADHD is a superpower from a different angle โ€” that the people loudest about ADHD being a superpower tend to be the people with the most money and the most privilege. Faraone agrees and goes further: the myth is toxic because it leaves a struggling person feeling they've failed to find a superpower they were told they had.

Dave shares how to find your superpower in his TEDx talk about ADHD.

Also in this episode:

How a proper diagnosis is actually made (and why a free ADHD quiz online is a screening test, not a diagnosis), why sleep apnea gets misdiagnosed as ADHD, the default mode network and getting distracted by your own ideas, what stimulants actually do to the dopamine transporter, why amphetamines are illegal in Japan, and whether the FDA and CDC can still be trusted.

A note on audio: Dave recorded his side on AirPods by mistake. His guest sounds great; Dave doesn't. The content was too good to lose, so here we are. ยฏ\_(ใƒ„)_/ยฏ

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Dave

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The "Wise No": Managing Impulsivity, Craving, and Negative Self-Talk with Joseph Goldstein.